Informs Annual Meeting Phoenix 2018

INFORMS Phoenix – 2018

KEYNOTE

Tuesday, 3:40PM - 4:30PM

5 - A Discrete-event Simulation Approach for Modeling Human Body Glucose Metabolism Buket Aydas, University of Wisconsin-Milwaukee, 3200 N. Crammer St., Milwaukee, WI, 53211, United States, Mukul Goyal This study describes CarbMetSim, a discrete-event simulator that tracks the blood glucose level of a person in response to a timed sequence of diet and exercise activities. CarbMetSim implements broader aspects of carbohydrate metabolism in human beings with the objective of capturing the average impact of various diet/exercise activities on the blood glucose level. Key organs are implemented to the extent necessary to capture their impact on the production and consumption of glucose. Key metabolic pathways are accounted for by using the published values of the average flux along these pathways in the operation of different organs. CarbMetSim has the ability to model different levels of diabetes. 6 - Verify an Anesthesia Approach for the Target Blood Volume Control Anesthesia is an inevitable and critical procedure during an operation, resulting in the amount of blood loss directly. This study verifies a typical anesthesia approach for liver surgeries, which can reach the target blood volume control, through simulation models. We provide clinical guidelines for training anesthetists and evaluating their performance. n TD84 Hyatt, Russell Practice- Innovation/ Entrepreneurship II Contributed Session Chair: Ping Deng, University of Science and Technology of China, No.96, Hefei, 230026, China 1 - Rights of First Negotiation and Rights of First Refusal in New Product Development Partnerships Strategic control rights such as the right of first negotiation (ROFN) and the right of first refusal (ROFR) are commonly used in the pharmaceutical industry for creating partnerships between biotech and pharmaceutical firms. We build a stylized principal-agent model to study the contract design problem with the ROFN and ROFR. We investigate the efficacy of different control rights being offered from the innovator’s (biotech firm) perspective. We also investigate the role of strategic control rights in resolving the adverse selection problem for the innovator. Our results address an important issue, viz., which control right to offer under which circumstances. 2 - Economies Before Scale: Learning, Survival, and Productivity of Young Plants in the Age of Cloud Computing Wang Jin, Research Associate, MIT, Cambridge, MA, United States, Kristina Steffenson McElheran Young firms are central to productivity and growth, yet they fail at high rates. Recent advances in how firms access information technology (IT) - in particular, cloud computing - have dramatically lowered the costs of learning about productivity-enhancing IT. Using Census Bureau data from 2006 to 2014, we find that young-plant failure rates fell 5% due to new IT services, while traditional IT proved risky. Conditional on survival, young plants enjoy much higher cloud- related productivity gains compared to older ones. We provide the first large-scale evidence concerning both the magnitude of and mechanisms behind cloud-driven productivity growth in the U.S. 3 - New Knowledge Availability, Intellectual Property Right Regimes and Technology-based Entrepreneurship in China Ping Deng, PhD Candidate, University of Science and Technology of China, Hefei, China, Jin Hong This study empirically investigates the contextual influence of intellectual property protection (IPR) on the use of new available knowledge by entrepreneurs in China’s high-tech industry. Using a unique database of China’s high-tech new formations from 2000 to 2008, we show that higher level investment in new knowledge is critical in encouraging creating high-tech ventures. However, stronger enforcement of IPRs negatively affects new knowledge availability. Industry heterogeneity analyses show that the need of IPR protection varies by industries. These findings contribute to understanding the influence of IPR protection on the technology-based entrepreneurial behavior in China. Guangyu Wan, Assistant Professor, Hunan University, #724, Admin Building, North Campus, Changsha, 410006, China, Bhattacharya Shantanu, Sameer Hasija, Niyazi Taneri Ting Wu, Nanjing University, Department of Mathematics, No 22 Hankou Road, Nanjing, 210093, China, Cheng Zhu

n Keynote – Tuesday West Bldg 301AB Keynote: Operational Innovation to Profitably Achieve Net Negative CO2 Emissions Keynote Session Chair: Ali E. Abbas, University of Southern California, Los Angeles, CA, 90089, United States 1 - Operational Innovation to Profitably Achieve Net Negative CO2 Emissions Erica Plambeck, Stanford University, Stanford, CA, 94305-7298, United States Operational innovation in the construction industry and the palm oil industry could increase profitability and reduce the CO2 emissions associated with those industries (perhaps even to net negative levels), and thus substantially reduce global anthropogenic CO2 emissions. I will describe new teaching materials and research that illustrate these hopeful prospects. Emerging Topic: Keynote Emerging Topic Session Chair: Anne G. Robinson, Verizon Wireless, Basking Ridge, NJ, 07920, United States 1 - FCC Edelman Reprise Karla L. Hoffman, George Mason University, Fairfax, VA, 22030, United States, khoffman@gmu.edu The Federal Communications Commission (FCC) recently completed the world’s first two-sided spectrum auction, reclaiming spectrum from TV broadcasters to meet exploding demand for wireless services. Operations research tools- including optimization, simulation, and SAT-solvers - were essential to both the design and implementation of the auction. The auction was one of the most successful in the FCC’s history, repurposing 84 MHz of spectrum and generating revenue of nearly $20 billion, including more than $10 billion in new capital for the broadcast TV industry and over $7 billion to pay down the U.S. deficit. n Keynote – Tuesday West Bldg 301D Keynote: Franz Edelman Award FCC

n Keynote – Tuesday West Bldg 301C Keynote: Wagner Prize Winner

Emerging Topic: Keynote Emerging Topic Session Chair: Patricia Neri, SAS Institute, Inc., Cary, NC, 27519, United States 1 - Wagner Prize Patricia Neri, SAS Institute, Inc., Cary, NC, 27519, United States The Daniel H. Wagner Prize is awarded for a paper and presentation that describe a real-world, successful application of operations research or advanced analytics. The prize criteria emphasize innovative, elegant mathematical modeling and clear exposition.

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